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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIK1
All Species:
10
Human Site:
Y272
Identified Species:
20
UniProt:
P39086
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39086
NP_000821.1
918
103981
Y272
L
D
L
E
L
Y
R
Y
S
G
V
N
M
T
G
Chimpanzee
Pan troglodytes
Q5IS46
956
107246
N264
S
L
V
D
D
R
V
N
I
L
G
F
S
I
F
Rhesus Macaque
Macaca mulatta
XP_001100491
918
103956
Y272
L
D
L
E
L
Y
R
Y
S
G
V
N
M
T
G
Dog
Lupus familis
XP_544843
923
104876
E269
P
H
V
S
S
I
I
E
K
W
S
M
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60934
836
95183
M246
I
L
K
Q
I
L
F
M
G
M
M
T
E
Y
Y
Rat
Rattus norvegicus
P22756
949
107822
Y272
L
D
L
E
L
Y
R
Y
S
G
V
N
M
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506390
892
100577
T268
T
G
F
R
I
L
N
T
E
N
S
Q
V
S
S
Chicken
Gallus gallus
P19439
487
54337
Frog
Xenopus laevis
Q91755
285
32023
Zebra Danio
Brachydanio rerio
Q68Y21
1009
113606
M275
M
D
V
Q
E
L
V
M
K
S
I
G
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03445
991
111650
V275
N
H
W
P
S
D
V
V
E
F
G
A
I
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34299
962
108124
F269
L
P
Y
D
Q
E
M
F
Q
N
G
N
I
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
99.7
90.3
N.A.
80.6
89.7
N.A.
75
23
22.7
27.3
N.A.
33.4
N.A.
29.7
N.A.
Protein Similarity:
100
59
99.8
92.8
N.A.
84.8
92.6
N.A.
85.7
35
25.8
45.7
N.A.
52.8
N.A.
50.3
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
100
N.A.
0
0
0
6.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
100
6.6
N.A.
26.6
100
N.A.
20
0
0
33.3
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
17
9
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
25
9
9
0
9
17
0
0
0
17
0
0
% E
% Phe:
0
0
9
0
0
0
9
9
0
9
0
9
0
0
9
% F
% Gly:
0
9
0
0
0
0
0
0
9
25
25
9
0
0
25
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
17
9
9
0
9
0
9
0
17
9
17
% I
% Lys:
0
0
9
0
0
0
0
0
17
0
0
0
0
0
0
% K
% Leu:
34
17
25
0
25
25
0
0
0
9
0
0
0
9
9
% L
% Met:
9
0
0
0
0
0
9
17
0
9
9
9
25
0
0
% M
% Asn:
9
0
0
0
0
0
9
9
0
17
0
34
0
17
0
% N
% Pro:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
9
0
0
0
9
0
0
9
0
0
0
% Q
% Arg:
0
0
0
9
0
9
25
0
0
0
0
0
9
9
0
% R
% Ser:
9
0
0
9
17
0
0
0
25
9
17
0
9
9
9
% S
% Thr:
9
0
0
0
0
0
0
9
0
0
0
9
0
25
9
% T
% Val:
0
0
25
0
0
0
25
9
0
0
25
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
25
0
25
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _